Abstract
Biosensors are sensitive and can be used as disposable sensors for environmental control. These biosensors are based either on inhibition of acyl cholinesterases acetylcholinesterase or butyrylcholinesterase) by organophosphorus compounds or on inhibition of enzymes phosphatases (acid or alkaline) or on direct detection of organophosphorus compounds by organophosphorus hydrolase. The state-of-the-art of the three types of biosensors will be presented in this paper and a particular development will be done on our work on ENFET (Enzymatic Field Effect Transistor) biosensors.
Highlights
Organophophorus compounds are, among the known substances, the most toxic
Biosensors based on inhibition of acylcholinesterases are sensitive and very suitable for use as disposable sensors
Inhibition of enzyme is made directly in effluent itself and detection is performed in a buffer solution where activity of enzyme is optimum
Summary
Organophophorus compounds are, among the known substances, the most toxic. They are used as pesticides, insecticides and chemical war agents. The high toxicity of organophosphorus neurotoxics and their large use in modern agriculture practices, has increased public concerns They have incited the development of technologies to treat effluents generated at both the producer and consumer levels. The techniques of gas chromatography, liquid chromatography and thin film chromatography coupled with different detectors and the different types of spectroscopy are the most commonly used methods These techniques are time consuming, expensive and demand a qualified and Sensors 2001, 1 experienced staff and cannot be used for continuous monitoring. Biological techniques such as immunoassays and inhibition of cholinesterase activity by colorimetric techniques are used for the determination of organophosphorus compounds. The state-of-the-art of the three types of biosensors will be presented in this paper and a particular development will be done on our work on ENFET (Enzymatic Field Effect Transistor) biosensors
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
