Abstract
(1) Background: The fascinating properties of currently synthesized aerogels associated with the flexible approach of sol-gel chemistry play an important role in the emergence of special biomedical applications. Although it is increasingly known and mentioned, the potential of aerogels in the medical field is not sufficiently explored. Interest in aerogels has increased greatly in recent decades due to their special properties, such as high surface area, excellent thermal and acoustic properties, low density and thermal conductivity, high porosity, flame resistance and humidity, and low refractive index and dielectric constant. On the other hand, high manufacturing costs and poor mechanical strength limit the growth of the market. (2) Results: In this paper, we analyze more than 180 articles from recent literature studies focused on the dynamics of aerogels research to summarize the technologies used in manufacturing and the properties of materials based on natural polymers from renewable sources. Biomedical applications of these bio-based materials are also introduced. (3) Conclusions: Due to their complementary functionalities (bioactivity, biocompatibility, biodegradability, and unique chemistry), bio-based materials provide a vast capability for utilization in the field of interdisciplinary and multidisciplinary scientific research.
Highlights
The interest in aerogels has been dating for a long time, but products based on such compounds have increased greatly in the last few decades due to their special properties
Aerogel materials prompted a growing interest in pharmaceutical sciences for drug delivery applications owing to their high surface areas, high porosity, open-pore structures, increased bioavailability for low solubility drugs, improved stability, and release kinetics [133]
In the context of vast domains of applicability of the aerogels as nanostructured materials presented in the reviews, the full potential of these materials is still to be assessed for various technology sectors
Summary
The interest in aerogels has been dating for a long time, but products based on such compounds have increased greatly in the last few decades due to their special properties. ILS are organic salts that are liquids the other hand, one of the physical properties of ILS that can influence the surface area of the materials is the melting point. Lopes et al have highlighted in their study the influence of such a property on preparing porous cellulose-based aerogels. They observed that when ILS with lower melting points, such as 1-ethyl-3-methylimidzolium acetate (EmimAc) or 1-ethyl-3-methylimidazolium diethyl pPhhoarsmpahceautteics(E20m20i,m12D, 4E4P9 ), were utilized, aerogels with higher surface areas were formed [34]. About 190 articles from recent literature and studies on the dynamics of aerogel research were reviewed to summarize the technologies used in the manufacture and properties of the materials based on natural polymers from renewable sources. The applications in the biomedical field of these bio-based materials were introduced
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