Abstract
This paper explores the pathophysiology of chronic and acquired premature ejaculation. Through a detailed analysis of multiple studies and research findings, we present a comprehensive description of the factors associated with this condition, bringing forth the latest information from the scientific literature. Thus, we outline a detailed picture of the neurological, endocrine, urological, and psychological mechanisms involved in the development and persistence of premature ejaculation, highlighting the complex interactions between them. The theoretical approach of this paper provides a solid perspective on the progress in understanding premature ejaculation, contributing to the foundation of future research and the optimization of therapeutic intervention strategies. By synthesizing existing information, this work aims to be an essential guide for healthcare professionals and researchers involved in the study of premature ejaculation.
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