Abstract

Nitriles and amide of nicotinic acid were synthesized by Knoevenagel reactions, nucleophilic vinyl substitution (SNVin), and alkylation. The structure of (1-amino-5-phenyl-5,6,7,8-tetrahydrothieno[2,3- c ]isoquinolin-2-yl)(phenyl)methanone was studied by X-ray analysis.

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