Abstract
The aim of the study was to upgrade the Horia Hulubei National Institute for Physics and Nuclear Engineering existing facility - a 3 MV TandetronTM accelerator - to be used in radiobiology experiments. Irradiations were performed with 1.95 MeV protons (beam with uniform distribution over a 30 mm2). Particle fluence was determined with plastic track detectors and live monitored using Rutherford Backscattering Spectrometry technique. Absolute and relative dose (Advanced Markus ion chamber) and the lateral quality of the irradiation spot (radiochromic film) were measured. The dosimetric measurements were confirmed by Geant4 simulations of the dose averaged Linear Energy Transfer, the Bragg peak profile and the beam lateral energy distribution. A complete setup for exposing in vitro cell cultures to the particle beams was constructed from scratch. Preliminary data of survival rate of V79 fibroblast cells are reported. The obtained results are similarly with data reported using other proton beam facilities.
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