Abstract
Inferring the geographic origin of an individual by analyzing DNA from a crime stain will help the investigators to find an unknown suspect and to save time in case of mass screening. Even though the non-recombining markers from the Y-chromosome and the mitochondrial DNA (mtDNA) are useful to determine an ethnic origin and tracing migration population, their analysis could lead to conflicting results in case of admixed populations. Therefore, autosomal markers appear to be more suitable for the forensic field. We have selected 32 SNPs loci that exhibit a large difference in their allele frequency distribution between three major population groups (African (Af), east Asian (As) and European (Eur)). The most informative nine markers ( F ST higher than 0.80) are sufficient to have a correct population assignment. The use of the complete panel of 32 SNPs refines the percentage of membership, determine genome admixture and allows a population group classification higher than three.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have