Abstract
Membranes are used for guided bone regeneration (GBR) in bone defects. Resorbable membranes of collagen or aliphatic polyesters that do not require secondary surgery for removal, unlike non-resorbable membranes, have been marketed for GBR. Platelet rich fibrin membrane and silk-based membranes have recently been assessed as membranes for GBR. Studies have been conducted on resorbable membranes with new materials to improve physical properties and bone regeneration without any adverse inflammatory reactions. However, clinical research data remain limited. More studies are needed to commercialize such membranes.
Highlights
Guided bone regeneration (GBR) is a widely used technique for bone regeneration on alveolar bone defects [1,2]
The purpose of this paper is to selectively review new resorbable membrane materials used for GBR
Collagen membrane has the advantages of low antigenicity, high biocompatibility, and excellent cell affinity, but pure collagen has the disadvantage of being difficult to handle due to a paucity of physical properties, and it is degraded quickly [12,13,14]
Summary
Guided bone regeneration (GBR) is a widely used technique for bone regeneration on alveolar bone defects [1,2]. GBR uses a membrane as a physical barrier to prevent epithelial and connective tissue in the bone defect [3,4,5,6]. The selection criteria for a membrane used for GBR are important [7]. Ideal membrane characteristics include tissue integration, cell occlusivity, clinical manageability, space-making, and biocompatibility [8,9]. GBR membranes can be divided into two types—resorbable and non-resorbable—depending on their degradation characteristics [10]. Non-resorbable membranes have the disadvantage of requiring secondary surgery for removal that can cause additional pain, discomfort, infection, and economic burden [3]. Resorbable membranes have been developed to overcome this problem [1]. The purpose of this paper is to selectively review new resorbable membrane materials used for GBR. The changes in characteristics of membranes by adding additives to commercial membranes are described, unlike previous papers
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