Abstract
2-Hydroxymethylindole reacts with l-dehydroascorbic acid under mild conditions to give (3 R,3a R,10c S)-3-[(1 S)-1,2-dihydroxyethyl]-3a,10c-dihydroxy-3a,5,6,10c-tetrahydrofuro[3′,4′:5,6]pyrano[3,4- b]indol-1(3 H)-one. Its tosyl derivative undergoes cyclization to form a pentacyclic ketal derivative.
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