Abstract
Abstract Four new pregnane steroids, ceratosteroid A (1), B (2), C (3), and D (4), were isolated from the Formosan red alga Ceratodictyon spongiosum and symbiotic sponge Sigmadocia symbiotica. The structures were elucidated by 1D and 2D NMR spectral analyses. Compounds 2 and 4 showed cytotoxicity against P-388 cell line.
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