Abstract
AbstractA new four step synthesis of prazosin, 2‐[4‐(2‐furoyl)piperazin‐l‐yl]‐4‐amino‐6,7‐dimethoxyquinazoline, has been described. The method is also adaptable for the preparation of other substituted 4‐aminoquinazolines. The yields are good in every step and the reactions are performed with ease. Prazosin hydrochloride of high purity is obtained directly in the last step.
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