Abstract

Aclidinium is a new anticholinergic agent for maintenance therapy of chronic obstructive pulmonary disease (COPD). Pharmacokinetic properties of aclidinium provide higher safety profile and lower risk of extrapulmonary adverse effects. In clinical phase III studies, aclidinium significantly increased lung function, reduced clinical symptoms and improved quality of life in patients with COPD. The aim of this review was to analyze clinical trials evaluating pharmacokinetics, clinical efficacy and safety of inhaled aclidinium bromide.

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