Abstract
Hard-to-heal wounds continue to be a challenge in the everyday surgical practice. Their treatment is time-consuming, expensive and in many cases requires interdisciplinary assessment. Therapy option include properly selected surgical procedures and dressings combined with systemic antibiotherapy. Application of vacuum assisted closure (VAC) facilitates the evacuation of pathological discharge, reduces tissue oedema and eliminates bacterial biofilm. Complementary administration of antibiotics to control chronic infection relies today in most cases on vancomycin, ciprofloxacin or piperacillin with tazobactam, with good clinical effect. 
 An alternative to antibiotics against MRSA, administered at hospitals might be dalbavancin, a new generation lipoglycopeptide, which belongs to the same class as vancomycin. Introduction of dalbavancin and VAC might be an alternative to traditional methods of therapy.
Highlights
EpidemiologyE XTENSIVE hard-to-heal wounds represent a significant problem in everyday surgical practice
Hard-to-heal wounds continue to be a challenge in the everyday surgical practice
An alternative to antibiotics against methicillinresistant S. aureus (MRSA), administered at hospitals might be dalbavancin, a new generation lipoglycopeptide, which belongs to the same class as vancomycin
Summary
E XTENSIVE hard-to-heal wounds represent a significant problem in everyday surgical practice. Hard-to-heal wounds are referred to as so-called “silent epidemic” which affects, according to various estimates, even 1-2% of the population in developed countries. In Scandinavian countries, spending related to the treatment of chronic wounds accounts for 2-4% of the health care budget.[1, 2]. Multicenter experiences indicate that dealing with chronic wounds calls for a comprehensive approach and requires a holistic assessment of the problem. This work did not receive any financial support. Author affiliations: Department of General, Endocrinological Surgery and Gastroenterological Oncology Poznan University of Medical Sciences, Poland , (JC, JP, TB)
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
