New peptides against B16F10 interfere in cell cycle of melanoma cells

Abstract

Peptides have fantastic functions; they can act interfering in various cellular mechanisms such as the cell cycle. Furthermore, because of their high specificity, peptides can be used in antitumor therapy against specific targets. In this work we describe the in vitro action of four antitumor peptide against B16F10 melanoma cells, obtained from immunoglobulin genes. As a result, we show that peptides interfered in the cell cycle of B16F10 cells. In conclusion the present article describes a molecule from immunoglobulin with future potential for in vivo therapeutic test.