New Parameters Derived from Tablet Compression Curves. Part II. Force-Displacement Curve

Abstract

Previously, many authors have described different types of parameters derived from tablet compression force-time curves. In this study, a great number of new compression parameters were calculated from tablet force-displacement curves. Tablets were made with an instrumented eccentric tablet machine using three different compression forces and three compression speeds, and α-lactose monohydrate as a model material. The results showed that the presented new force-displacement parameters explain the compression phenomenon from different points of view. The final usefulness of these parameters together should be studied in the future with different types of materials. It is expected that many of the presented parameters can give valuable information on tablet compression and can lay the foundation for understanding of the compression phenomenon and bond formation during tableting