New opportunities for mucioactive therapy in patients with pathology of the respiratory tract

Abstract

The most common cause of patients referring to primary care physicians are respiratory diseases. Anatomical and physiological features of the human respiratory system and the type of etiotropic agent determine the characteristic features of the pathogenesis of respiratory pathology. The possibility of self-purification of the respiratory tract is of significant clinical importance - mucociliary clearance, but during the course of respiratory inflammatory diseases, the effectiveness of such purification suffers significantly due to the formation of edema and the increased production of a secretion more dense than the physiological norm provides. Almost all diseases of the upper and lower respiratory tract are accompanied by violations of the composition and rheological properties of the secretion and difficulties in its evacuation. The use of mucoactive drugs in the treatment of patients with inflammatory pathology of the respiratory tract has a tangible economic and clinical effect, reducing the duration of the disease, the need for systemic antibiotic therapy, the frequency and severity of relapses, a positive effect on the number of complications and quality of life. The drug Elmultsin® (erdosteinе), produced by the Russian pharmaceutical company «Obolenskoye», is a representative of a group of secretolytics and respiratory motor function stimulants, is promising for use in the treatment of patients with respiratory diseases accompanied by the formation of viscous sputum, including in conditions of adverse environmental conditions.