Abstract
A novel hydrophobic natural deep eutectic solvent (NADES) was designed and prepared to selectively enrich biphenolic compounds. The NADES was prepared by blending different molar ratios of octanol and menthol. Various important parameters that influence the extraction efficiency were optimized, including the composition of NADES components, volume, the influence of salt, extraction time, and pH. The experimental results demonstrated that the method exhibited a wide linear range (5–1000 μg/L) with a linear correlation coefficient (R2) exceeding 0.995. The limits of detection (LOD) and quantification (LOQ) ranged from 0.44 to 0.96 μg L−1 and 1.33 to 3.16 μg L−1, respectively. Furthermore, quantum chemical calculations were utilized to analyze the electrostatic potentials of menthol, octanol, water, and the three biphenolic compounds, providing insights into the extraction mechanism of NADESs. The environmental impact of the proposed method was assessed using the ComplexGAPI and Whiteness method, revealing its eco-friendliness. Finally, the method was successfully employed for the extraction and determination of the three bisphenols in beverage samples.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
