Abstract
<h3>To the Editor:</h3> —Recently inThe Journal(March 7, 1914, p. 800) there appeared an abstract of a preliminary report on this subject by Dr. I. S. Kahn of San Antonio, Tex. Dr. Kahn brings forward the theory that typhoid patients or those who have recovered from typhoid react to small doses of typhoid vaccine in a manner similar to that in which patients suffering from tuberculosis react to tuberculin. This theory is wrong. Typhoid patients do not give a reaction to minute amounts of typhoid vaccine, as their serum contains an antibody brought into play by their attack of fever. The body reacts against the introduction of a foreign protein (typhoid bacilli). In 1911, I published a skin-reaction test based on this theory of antibody in the system of those suffering from typhoid fever (<i>Med. Rec.</i>, New York, Dec. 31, 1911). The typhoid patient gives no reaction to the
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