Abstract
Trimethyl chitosan ammonium iodide was obtained by reaction of a low acetyl content chitosan with methyl iodide and sodium hydroxide under controlled conditions. The role of sodium iodide as an electrostatic charges screening salt is discussed. The reaction was performed in several steps to obtain derivatives of chitosan at various degrees of quaternization with a limit value near 64%. For a degree of quaternization greater than 25%, these polymers are soluble in water, whatever the pH.
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