Abstract
IT IS KNOWN that the administration of tetracycline results in visible yellow fluorescence of tumor tissue. 1 The purpose of this paper is to communicate our experiences in the recovery of fluorescent material from the gastric contents in subjects with known bronchogenic carcinoma. Method Thirty male patients at the Veterans Administration Hospital, Oklahoma City, were studied. Fifteen of these patients had histologically proven bronchogenic carcinomas at different stages of the disease. The other 15 patients were diagnosed as having acute or chronic pulmonary diseases other than carcinoma. All study subjects received 1.0 gm of oxytetracycline in divided doses, orally, for five consecutive days, followed by a one day interval to allow for the disappearance of any residual tetracycline particles in the stomach and for the elimination of fluorescence from normal tissues. An overnight sputum specimen was obtained for exfoliative cytology. In the early morning of the seventh day, the stomach was
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