Abstract

Neuraminidase (NA), a key enzyme in viral replication and spread, is the first-line drug target to combat influenza. Based on a shape-focused virtual screening approach, the roots of Glycyrrhiza glabra L. (licorice) were identified as plant material with an accumulation of molecules that show 3D similarities to previously discovered influenza NA inhibitors [1]. Moreover, licorice is the most frequently cited herb in TCM for treating respiratory tract infections [2].

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