New insight into the concentration-dependent removal of multiple antibiotics by Chlorella sorokiniana

Abstract

Microalgae have attracted increasing attention as an environmentally friendly treatment for antibiotics. However, the effect of antibiotic concentration on the removal ability of microalgae with the underlying mechanisms remains unclear. Thus, this work investigates the removal of tetracycline (TET), sulfathiazole (STZ), and ciprofloxacin (CIP) at different concentrations using Chlorella sorokiniana. The results indicate that microalgae have a concentration-dependent effect on antibiotic removal; however, the removal trends for the three antibiotics differed significantly. Specifically, TET showed nearly 100% removal efficiency at any concentration. The high concentration of STZ inhibited microalgal photosynthesis and induced the production of ROS, leading to antioxidant damage and inhibiting removal efficiency. Conversely, CIP enhanced the ability of microalgae to remove CIP by inducing a dual peroxidase and cytochrome p450 enzyme response. Furthermore, the economic analysis demonstrated that microalgae treatment antibiotics were calculated to be 4.93€/m3, which becomes cheaper than the other microalgae water treatment process.