Abstract
By exploiting the reactivity of 7-alkyl-3-chloro-4-cyano-1-hydrazino-5,6,7,8-tetrahydro-2,7-naphthyridines 5 some 7-alkyl-1-azido-3-chloro-4-cyano-5,6,7,8-tetrahydro-2,7-naphthyridines 6 were synthesized. Looking at their chemical properties we have ascertained that in these compounds the azide/tetrazole equilibrium is completely shifted towards the azido form (both in solid state and in solution). Their behaviour with some amines was tested as well. Moreover by exploiting the reactivity of the chlorine and of the nitrile group we have fused on the pyridine system two new rings (pyrazole or thiophene), thus obtaining previously unknown heterocyclic systems (10 and 11). Interestingly, in these new systems, the position of the above equilibrium is reversed.
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