Abstract
Methods have been developed for the synthesis of new substituted 7,8,9,10-tetrahydro[1,2,4]triazolo-[3,4-a][2,7]naphthyridines from 3-chloro-1-hydrazino-7-methyl-5,6,7,8-tetrahydro-[2,7]naphthyridine-4-carbonitrile. It was shown that on heating in an amine (ethanolamine, pyrrolidine, 2-hydroxy-propylamine), they undergo a Dimroth rearrangement at the triazole fragment, being converted into 7,8,9,10-tetrahydro[1,2,4]triazolo[5,1-a][2,7]naphthyridine derivatives. Authors: S. N. Sirakanyan, N. G. Avetisyan, and A. S. Noravyan. English Translation in Chemistry of Heterocyclic Compounds , 2012, 48 (3), pp 470-475 http://link.springer.com/article/10.1007/s10593-012-1017-z
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