Abstract
Our previous study verified that the waste skin of cocoa (Theobroma cacao L) fruit or waste cocoa pod husks had the efficacy to overcome hair loss or alopecia. This study aims to determine the formula and activity of hair cream of cocoa pod peel water fraction, which is effective in stimulating hair growth. Activity testing uses the modified Tanaka method. The results showed that the cocoa husk wastewater fraction could be formulated into hair cream, but there were changes in viscosity and pH after the freeze-thaw test, but still within the allowed limit. The hair cream water fraction gel stimulated hair growth activity based on the hair length data with a significant difference in concentration of the preparation. The best activity in hair cream preparation was at 12.5% concentration. In addition, there were no signs of irritation to the rabbit's skin where hair cream preparation was applied. The results of this study indicated that cocoa fruit peel cream can be used for antialopecia treatments.
Highlights
Research on synthetic treatments is still in development, but it should be noted that the side effects of synthetic drugs cannot be ignored. us, herbal medicine is a possible alternative to synthetic drugs
Components that dissolve in the nonpolar phase will dissolve in n-hexane, while the polar phase will dissolve in distilled water. e water fraction had the most concentrated color, while the ethyl acetate fraction was yellow and the n-hexane fraction was pale yellow. e water fractions of the cocoa pods were concentrated using an evaporator and a waterbath, so that the solvent could evaporate to form a thick extract. e thick extract of the cocoa pod skin was dark brown with a characteristic odor [9]
The cream was directly formed during the process of mixing the water and oil phases with constant stirring at 70°C. e cream base was white, and the color changed to light brown after the addition of the water fraction of the cocoa pods. e result of the cream of water fraction of cocoa pods had a white and thick consistency
Summary
Hair is one of the body’s vital parts because it is an essential factor in appearance and confidence. e role of hair is quite important both in humans and animals due to its functions to protect from sunlight, UV rays, regulate temperature, and sweat evaporation. Alopecia is baldness, which involves absence or hair loss, especially the part of the head [1–3]. Traditional medicine is quite popular, based on the study results, not causing too many side effects [5]. Indonesia is the third largest cocoa ( eobroma cacao L.) producing country globally after Ivory Coast and Ghana, with production that continues to grow every year [6, 7]. E skin of cocoa fruit is usually boiled, and the water is clamped and taped to treat the head of children who are corroded and bald. E absence of scientific research on the properties of the cocoa skin is the rationale for this research. Our previous study verified that the waste skin of cocoa ( eobroma cacao L) fruit or waste cocoa pod husks had the efficacy to overcome hair loss or alopecia [9]. Materials and Methods e research methods include collecting cocoa pods, processing, cocoa pods, extraction using 70% ethanol solvent by maceration, fractionation of cocoa pod extract using the ECC (liquid-liquid extraction) method, formulation of cream preparations of cocoa rind water fraction, evaluation of cream preparation formula, and cream activity test for male rabbits based on the Tanaka method (1980) [12], irritation test, and data processing
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