Abstract
Abstract Five cases of congenital nonspherocytic hemolytic disease were studied. In 3 of them, new glucose-6-phosphate dehydrogenase variants were detected while the common Mediterranean variant was found in the other 2. An additional variant was characterized from the blood of a patient who had a hemolytic episode during infectious hepatitis. No correlation was found between the characteristics of the variant enzymes and the clinical manifestations of the disease.
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