New Findings on Energy Balance and Established Wisdom

Abstract

Background. Energy balance in blood and body may differ for a day or two although compensating in a month. Most people (60%) maintain a positive energy balance and a high blood glucose (BG) high energy availability in blood and high resting metabolic rate that correspond to insulin resistance/fattening and ill health. A meal/satiety pattern dictated by the rhythmic arousal of Initial Hunger (IH and IHMP) improved exhaustion of the energy consumed in previous meals and decreased high energy intake, high preprandial BG, high resting metabolic rate (RMR), insulin resistance, overall subclinical inflammation, vascular risks, deteriorations and functional disorders. Methods. We defined Initial Hunger as sensations that spontaneously arise after eating suspension. IH consistently arouse in different groups when BG declined toward 76.6 ± 3.7 mg/dL. A week diary reported assessments of IH and preprandial BG measurements before the three main meals. Mean BG in a week was stratified within normal BG limits, but different subjects pertained to different strata. Thirty-one untrained control adults maintained his/her own mean and BG stratum for five months. After training, these subjects changed his/her own mean BG to the stratum that was associated with IHMP. Measurements reported by diary, of RMR and of total energy expenditure demonstrated this stratum change. From recruitment, the mean decrease was 15.4% by indirect calorimetry and 15.5% by doubly labeled water in a total of 24 toddlers (P < 0.001). Mean BG thus assessed the deviation of a meal pattern from the mean BG associated with IH (IHMP). Results. In San Diego ASN 2014, we showed the effectiveness of IHMP on regression of fattening/insulin resistance for a long term in 181 adults of mixed body weight who had bowel functional disorders and were clinically normal. However we had earlier designed IHMP for a broader aim as compared to a body loss device. We wanted to educate children and future adults to an intestinal low immune involvement and to the best fitting of intake to body regulations. Thus, we tried to publish the recovery of diarrheic malnourished infants by IHMP in an American Society for Nutrition (ASN) Journal. Subjects were aged less than 15 months, had lower body weight per age than 70% and recovered through many months and years. This aim was right opposite to weight loss. The ASN Journal rejected the publication as findings of clinical but no nutritional interest. Med Crave promptly published the findings. In a broader thought, the ASN Journal protected the established assistance beliefs and trusts from the confounding intrusion of an innovative, self-help system (IHMP).