Abstract
A simple, sensitive, selective, accurate and economical spectrophoto-metric method have been described in the present work for the deter-mination of danazol in bulk drug and pharmaceutical formulations (tablets). Method is based on the formation of yellow coloured ion-association complexes between danazol and alizarine red S in acid medium followed by their extraction with chloroform, exhibiting absorption maxima at 430 nm, and obeying Beer′s law in the concen-tration range of 5-30 μg/mL. Statistical analysis of the results of the proposed methods reveals high accuracy and good precision. The proposed methods could be successfully extended to the commercial pharmaceutical formulations containing danazol.
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