Abstract

New Era for Biocomputing Fast and cheaper Next Generation Sequencing (NGS) technologies will generate unprecedentedly massive (thousands or even ten thousands of individuals) and highly-dimensional (ten or even dozens of millions) genomic and epigenomic variation data that allow nearly complete evaluation of genomic and epigenomic variation including common and rare variants, insertion/deletion, CNVs, mRNA by sequencing (RNA-seq), microRNA by sequencing (mRNA-seq), methylation by sequencing (methylation-seq) and Chip-seq. Analysis of these extremely big and diverse types of data sets provide powerful tools to comprehensively understand the genome and epigenomes.

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