Abstract
A phytochemical investigation of the leaves of Erythrophleum fordii Oliv. has led to the isolation of three new cassaine-type diterpenoids, erythrofordin A ( 1), erythrofordin B ( 2) and erythrofordin C ( 3), as well as a norcassaine diterpenoid with a novel skeleton, norerythrofordin A ( 4), and 27 known compounds ( 5– 31). The structures of 1– 4 were elucidated on the basis of spectroscopic analysis. Selected compounds from this plant were examined for anti-inflammatory activity. Taraxerol ( 16) displayed potent NO-reducing activity in microglial cells, and gallic acid ( 27) exhibited excellent DPPH radical-scavenging effects.
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