New developments in optical coherence tomography

Abstract

AbstractPurpose Optical coherence tomography (OCT) has become a standard tool in imaging the retina, the optic nerve head and the anterior segment of the eye. In the recent years much effort was directed towards improving the acquisition speed and the resolution of the technique. In addition, functional extensions of the technique were presented.Methods Ultrahigh‐speed swept sources can be used to improve A‐scan rate in OCT, a technique also called optical frequency domain imaging. Increasing the bandwidth can improve longitudinal resolution in OCT and longer wavelengths in the near infrared improve penetration depth. Adaptive optics OCT improves transversal resolution. Functional extensions include measurement of blood flow and oxygenation.Results High‐speed imaging allows for three‐dimensional imaging of the posterior and anterior segment of the eye. Using adaptive optics volumetric cellular resolution imaging becomes possible. 1050 nm OCT allows for visualization of the sclera and therefore measurement of choroidal thickness. Functional OCT provides insight into retinal metabolism.Conclusion Improvements and extensions of OCT have been reported that will find its way into clinical routine. This is expected to result in improved understanding of retinal and optic nerve head disease.