Abstract
PTC taste thresholds were determined in 229 Caucasoid and Negroid patients with thyroid diseases and 252 controls carefully matched in relation to sex, age, race, grandparents' nationality and socioeconomic level. The majority of the affected persons had either multinodular or diffuse goiter, but individuals with uninodular goiter or hypothyroidism were also studied. Among multinodular goiter patients there is a slightly higher prevalence of non-tasters (26%) and among diffuse goiter persons a lower one (15%) as compared to controls (21%). A review of all previous studies dealing with these associations was also made; the same tendency was observed among them. The use of Woolf's method showed that these relationships were statistically significant, with no indication of heterogeneity.
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