Abstract
AbstractFour new myrsinol diterpenes, proliferins A–D (1–4, resp.) were isolated from the EtOH extracts of the roots of Euphorbia prolifera, along with four known compounds, euphorprolitherin B (5), euphorprolitherin D (6), SPr5 (7), and 14‐desoxo‐3‐O‐propionyl‐5,15‐di‐O‐acetyl‐7‐O‐nicotinoylmyrsinol‐14β‐acetate (8). Their structures were established on the basis of spectroscopic methods, including HR‐ESI‐MS, and 1D‐ and 2D‐NMR techniques. The cytotoxicity of compounds 1, 3, and 4 against cancer cells was evaluated, with compound 1 being active against A2780 cancer cells.
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