New cyclohexylethanoids from the leaves of Clerodendrum trichotomum

Abstract

A series of cyclohexylethanoids, including two new compounds, 1-hydroxy-1-(8-palmitoyloxyethyl) cyclohexanone (1) and 5-O-butyl cleroindin D (2), together with five known ones, rengyolone (3), cleroindin C (4), cleroindin B (5), rengyol (6) and isorengyol (7), were isolated from the leaves of Clerodendrum trichotomum. Their structures were elucidated on the basis of spectroscopic analyses and by comparison of their NMR data with those in the literatures. Compounds 1 and 2 were evaluated for their cytotoxicity against A549 human tumor cell line.