Abstract

A one-pot three or four component reaction of wide range of aromatic aldehydes, benzil, aliphatic and aromatic primary amines and ammonium acetate is reported for the synthesis of tri/tetra-substituted imidazoles under solvent-free conditions. Indium (III) trifluoromethanesulfonate and magnesium sulfate heptahydrate as two highly efficient and recyclable catalysts perform a key factor to synthesis of imidazole derivatives with high yields.

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