New class of chiral, inclusion forming crystals with host molecules derived fromtrans-1,2-diaminocyclohexane

Abstract

Inclusion properties of several crystals containing as host molecules trans-1,2-diaminocyclohexane units connected by various types of aliphatic and aromatic spacers will be demonstrated [1]. The chiral host molecules are present either in a form of S-shaped chains, involved in face-stacking interactions with aromatic guest molecules, or in a form of rhombs or triangles, only very weakly interacting with the guests. Macrocyclic host molecules display versatile types of inclusion, which involve molecular inclusion, one-dimensional stack with chain molecules as guests in channels passing through the macrocyclic cavity, and various modifications of channel type inclusion with planar aromatic molecules as guests. Provided examples illustrate that the type of inclusion depends not only on the type of included solvent molecule(s) but also on the type of spacer in the host molecule and the host rigidity. The results presented highlight the potential of this new class of molecules as flexible hosts for various solvent molecules.