Abstract
Industrial biotechnology has not developed as fast as expected due to some challenges including the emergences of alternative energy sources, especially shale gas, natural gas hydrate (or gas hydrate) and sand oil et al. The weaknesses of microbial or enzymatic processes compared with the chemical processing also make industrial biotech products less competitive with the chemical ones. However, many opportunities are still there if industrial biotech processes can be as similar as the chemical ones. Taking advantages of the molecular biology and synthetic biology methods as well as changing process patterns, we can develop bioprocesses as competitive as chemical ones, these including the minimized cells, open and continuous fermentation processes et al.
Highlights
Industrial biotechnology has not developed as fast as expected due to some challenges including the emergences of alternative energy sources, especially shale gas, natural gas hydrate and sand oil et al The weaknesses of microbial or enzymatic processes compared with the chemical processing make industrial biotech products less competitive with the chemical ones
We believe that production of bulk chemicals including biofuels, polymeric materials and chemical agents using microorganisms or enzymes will provide low cost, environmentally friendly products to partially replace petro-chemicals products [1]
This looks not so easy to materialize due to the facts that: 1. Petroleum does not rise in price too much after 2008 financial crisis, other alternative energy sources, especially shale gas, natural gas hydrate and sand oil, have been discovered in large amount and their exploitations are increasingly moving toward a very competitive price; 2
Summary
Industrial biotechnology has not developed as fast as expected due to some challenges including the emergences of alternative energy sources, especially shale gas, natural gas hydrate (or gas hydrate) and sand oil et al The weaknesses of microbial or enzymatic processes compared with the chemical processing make industrial biotech products less competitive with the chemical ones. The commercialization of industrial biotechnology is not as fast as we expected. 5. Bioprocessing is still not as effective as chemical processing, resulting in high cost of bio-products (Table 1)
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