Abstract
Four new C16-noriridals (1–4) and two reported C16-noriridals (5–6), together with two new formyl-monocycloiridals (7–8) and three known monocycloiridals (9–11) were isolated from the rhizomes of Iris pseudoacorus. Irispseudoacorins A–D (1–4) and iridojaponals A–B (5–6) were C16-noriridals which shared a 6/5/7 tricyclic ring system (1–2, 5–6) or 6/5 tricyclic ring system (3–4). The formyl-monocycloiridals (7–8) were detected in the crude extracts of I. pseudoacorus by LC-MS analysis which suggested they were originated from natural sources rather than artificial products during the isolation. Their structures were determined by UV, IR, extensive NMR spectra and X-ray diffraction analyses. The known monocycloiridals 9–10 displayed pronounced cytotoxic effects against five human tumor cell lines. The IC50 values of 9 were ranging from 12.63 to 24.69μM.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
