New bright sensor with logic sense to detect early onset of malignancy: A direct observation

Abstract

Detection of tumour at its early onset is what the most desired in medical science. Biological malfunctions due to change in the cellular pH must be recognized quickly to start the appropriate treatment. Recently, we developed a unique pH sensitive gold nanocluster based bright sensor to detect sharp change in biological pH precisely in cellular environment. Here, we have explored the change in cellular pH through logic device for direct visualization in a very simple way. The logical response of an INHIBIT gate could identify the early onset of malignancy.