Abstract
A series of azo-azomethine compounds (Sb1- Sb5) have been synthesized with magnificent yield by condensation reaction of 4-((3-formyl-4-hydroxy-5-methoxyphenyl)diazenyl) enzenesulfonamide and aniline derivatives. The new azo compound was prepared from sulfanilamide by converting it to diazonium salt followed by coupling reaction with 2-hydroxy-3-methoxybenzaldehyde in alkaline medium. The structures of synthesized azo and azo-azomethine compounds have been established based on their spectral data (FT-IR,1HNMR,13CNMR)and elemental analysis (C,H,N).The purity of compound and evaluation of Rf value were determined by TLC. The antimicrobial activity of azo-azomethine compounds have been tested in vitro against bacteria (Staphylococcus aureus, Escherichia coli and Klepsilia pneumonia) and fungi (Candida glabrata, Candida albicane and Aspergillus niger) by agar diffusion method, to assess their inhibiting potential. Also the antioxidant efficiency of azo-azomethine compounds have been calculated.
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