Abstract

Malaria infection is initiated when a mosquito injects Plasmodium sporozoites into a mammalian host Sporozoites exhibit gliding motility both in vitro and in vivo This motility is associated with the secretion of at least two proteins circumsporozoite protein CSP and thrombospondin related anonymous protein TRAP Several molecules as for example albumin promote this motility by mechanisms which are not well understood The use of skin care products containing albumin is thus questionable Most of these ingredients are derived from soybean But there are other molecules which inhibit the motility of sporozoites

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