Abstract
AbstractThe copper‐mediated arylation of 7‐methylpyrimido[1,2‐a]purin‐10(3H)‐one (1) in dichloromethane or of N2‐(dimethylamino)methyleneguanine (2) in methanol in the presence of TMEDA as a base/ligand led to the preferential formation of 1‐aryl‐7‐methylpyrimido[1,2‐a]purin‐10(3H)‐ones (4) and 7‐aryl‐N2‐(dimethylamino)methyleneguanines (7), respectively. These compounds can be easily hydrolysed to the corresponding 7‐arylguanines. Similar arylation of N6‐(dimethylamino)methyleneadenine (15) in the presence of o‐phenanthroline instead of TMEDA afforded mainly 7‐aryladenines after hydrolysis.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callSimilar Papers
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
