New approach needed for diagnosis of human brucellosis in Morocco

Aicha Qasmaoui,Jamila Hamamouchi,Reda Charof,Farida Ohmani,Bouchra Belkadi,Karima Halout,S Bourekkadi,K Slimani,A Mokhtari,H Hami,A Soulaymani

doi:10.1051/e3sconf/202131901018

Abstract

Human brucellosis is an infectious disease, caused by different species of the genus Brucella. It is a mandatory notifiable disease in most countries, including Morocco, and thus requires special vigilance on the part of health agencies. Prevention of this disease is based on surveillance and prevention of risk factors. Its management is based on serological or other diagnostic tests. The National Laboratory of Epidemic Diseases received 17 blood samples of human origin for notified cases of brucellosis in a region of southern Morocco. Biological confirmation of these samples was performed by Rose Bengal test and ELISA IgM test. The results showed a positivity rate of 88% proving the important role of serological tests in the diagnosis of brucellosis. Other rapid and efficient techniques are becoming essential for the confirmation of cases, taking into account the advanced biosafety procedures for these highly infectious pathogens.

Highlights

Recognized as a re-emerging neglected disease, brucellosis is a zoonosis that affects humans and various domestic and wild animal species and remains a health problem in developing countries. [1,2]
Professional exposure and consumption of raw milk is one of the major sources of infection [6,7]. This disease is caused by gram-negative bacteria of the genus Brucella, which currently includes 12 species, of which only four are pathogenic for humans: Brucella abortus, Brucella canis, Brucella suis and Brucella melitensis [8,9]
It is a widespread disease in the world and one of the most important zoonoses worldwide in many countries, with 500 thousand cases reported each year according to World Health Organization (WHO) [10]

Summary

Introduction

Recognized as a re-emerging neglected disease, brucellosis is a zoonosis that affects humans and various domestic and wild animal species and remains a health problem in developing countries. [1,2]. Professional exposure and consumption of raw milk is one of the major sources of infection [6,7] This disease is caused by gram-negative bacteria of the genus Brucella, which currently includes 12 species, of which only four are pathogenic for humans: Brucella abortus, Brucella canis, Brucella suis and Brucella melitensis [8,9]. It is a widespread disease in the world and one of the most important zoonoses worldwide in many countries, with 500 thousand cases reported each year according to WHO [10].

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