Abstract
<h3>MAPHARSEN.</h3> The hemialcoholate of 3-amino-4-hydroxy phenylarsine oxide hydrochloride.—HCl.(NH<sub>2</sub>)C<sub>6</sub>H<sub>3</sub>(OH)AsO. ½C<sub>2</sub>H<sub>5</sub>OH. It contains approximately 29 per cent of trivalent arsenic. <i>Actions and Uses.</i>—Mapharsen is proposed for the treatment of syphilis. It is stated to exhibit a relatively constant parasiticidal value. It is claimed to have a rapidly beneficial effect, particularly on early syphilis, with disappearance of spirochetes, healing of lesions, and reversal of positive Wassermann reactions in a large percentage of cases. The reactions following the use of mapharsen have on the whole been less severe than those observed after the use of arsphenamine or neoarsphenamine. <i>Dosage.</i>—Intravenously, 0.03 Gm. for women and 0.04 Gm. for men, initially. The dose may be increased at the second injection to 0.04 Gm. for women and 0.06 Gm. for men. The maximum weekly dose, which should not be given any patient at the first
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