New agents for cutaneous photoprotection: derivatives of α-amino acids, 4-aminobenzoic and 4-methoxycinnamic acids

Abstract

Derivatives of sulfur-containing or sulfur-free α-amino acids, 4-aminobenzoic and 4-methoxycinnamic acids, which are potential sun screens, have been synthesized. The effects on melanin formation of 2 compounds ( 2 and 12) were studied via enzymatic reactions and cell culture. It was shown that these 2 compounds can enhance pigmentation.