Abstract

AbstractA base‐free and efficient tandem one‐pot α‐ketoamide bond formation via tert‐butyl hydroperoxide (TBHP) mediated oxidative coupling of α‐hydroxy acetophenones with primary and secondary amines under Ag(I)‐N‐Heterocyclic carbene (Ag(I)−NHC) catalysis in water was developed herein for the first time.

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