New advances on Au-magnetic organic hybrid core-shells in MRI, CT imaging, and drug delivery.

Fatemeh Mohajer,Alireza Badiei,Ghodsi Mohammadi Ziarani

doi:10.1039/d1ra00415h

Fatemeh Mohajer, Alireza Badiei + Show 1 more

Open Access

https://doi.org/10.1039/d1ra00415h

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Journal: RSC advances	Publication Date: Jan 1, 2021
Citations: 13	License type: CC BY 3.0

Affiliation: Alzahra University, University of Tehran

Abstract

Magnetic nanoparticles have been widely studied for various scientific and technological applications such as magnetic storage media, contrast agents for magnetic resonance imaging (MRI), biolabelling, separation of biomolecules, and magnetic-targeted drug delivery. A new strategy on Au–magnetic nano-hybrid core–shells was applied in MRI, CT imaging, and drug delivery, which has been received much attention nowadays. Herein, the designing of different magnetic core–shells with Au in MRI and cancer treatment is studied.

Highlights

There are various nanoparticles for medical applications, including carbon dots[1,2] and organic core/shell nanoparticles
The immunization of Au on Fe3O4@ promoted the optical properties of computed tomography (CT) and magnetic resonance imaging (MRI), which increased the resolution in 3D visual images in this process.[23,24]
In continuing our previous work,[26,55,56,57,58,59] we decided to introduce another application of core shells, including Au–magnetic organic hybrid in MRI, CT imaging, and drug delivery

Summary

Introduction

There are various nanoparticles for medical applications, including carbon dots[1,2] and organic core/shell nanoparticles. Core–shell (CS) nanostructures have received much attention due to the known constituents and con guration.[22] In this area, the immunization of Au on Fe3O4@ promoted the optical properties of computed tomography (CT) and MRI, which increased the resolution in 3D visual images in this process.[23,24] Through the importance of bioimaging in living cells, metal– organic frameworks (MOFs) were used which organic or inorganic uorescent compounds like quantum dots, uorescent dyes, nanosheets, and metal nanoclusters can provide modi ed MOFs to give uorescent nano-composites for an imaging agent.[25] In continuing our previous work,[26,55,56,57,58,59] we decided to introduce another application of core shells, including Au–magnetic organic hybrid in MRI, CT imaging, and drug delivery. Scheme 15 The preparation of I–Pd@Au–PEG–FA nanosheets

2.11. EGaIn–Au NPs

Conclusion

Conflicts of interest