Abstract
Two new acridine derivatives bearing azacrown or azathiacrown ligand were synthesized as fluorescent chemosensors for Hg 2+ and Cd 2+ in aqueous solution. Compounds 1 and 2 displayed selective CHEF (chelation enhanced fluorescence) effects with Hg 2+ or Cd 2+ among the metal ions examined. The practical use of these probes was demonstrated by their applications to the detection of Hg 2+ and Cd 2+ ions in mammalian cells.
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