Abstract
Six new acetylenic compounds, 1, 7–11, were isolated from the marin sponge Pellina triangulata. Structures were established using NMR spectroscopy and chemical degradation. Collisional activation decomposition (CAD) tandem mass spectrometry of the lithium adducts of the acetylenic compounds was applied to ascertain if charge-remote fragmentation would yield definitive information regarding the site of internal unsaturation in these polyfunctional compounds. Pellynic acid ( 1) inhibited inosine monophosphate dehydrogenase (LMPDH) in vitro. Six new acetylenic compounds, 1, 7–11, were isolated from the marine sponge Pellina triangulata. Structures were established using NMR spectroscopy, chemical degradation, and collisional activation decomposition (CAD) tandem mass spectrometry. Pellynic acid (1) inhibited IMPDH.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
