Abstract

Four new 8-hydroxybriarane diterpenoids, including junceols A–C ( 1– 3) and fragilide D ( 4), have been isolated from the gorgonian corals Junceella juncea and Junceella fragilis, respectively. The structures of briaranes 1– 4 were elucidated by the interpretations of spectral data analysis. Briaranes 1– 3 have displayed inhibitory effects on superoxide anion generation by human neutrophils.

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