Abstract
Nevus Lipomatosus Cutaneous Superficialis (NLCS) is an idiopathic, rare skin hamartoma. It occurs due to ectopic deposition of adipocytes in dermis. There are two main clinical forms of NLCS- classic and solitary. Both have different clinical presentations but histologically they show similar morphology characterised by bundles of mature adipocytes in the superficial and deep dermis separated by bundles of collagen. The hallmark of this lesion is absence of connection between subcutaneous fat and adipocyte clusters in dermis.Though NLCS is benign developmental disorder and remains static for a long time, it can be cosmetically unpleasant if grows to a large size. Herein, authors report a case of a 21-year-old male with a solitary painless pedunculated lump in right thigh for 10 years that clinically presented as giant lipoma due to its soft consistency, cut surface of the mass was yellow and fibrofatty. There was no connection of these adipocytes seen with the subcutaneous fat. Focal collections of adipocytes were also seen around the blood vessels. Sparse perivascular mononuclear inflammatory infiltrate also noted. Final diagnosis of NLCS was made.
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